Eli Lilly · Primly Community

Eli Lilly product manager interview questions: what they ask and how to frame your answers

jordan_pm · 4 replies

Went through Lilly's PM loop in late 2025 for a director-level digital product role. Coming from B2C SaaS into pharma was a bit of a translation exercise. Sharing what I learned.

Lilly's PM interviews are not the classic PM meta-framework grind. They're not asking you to estimate the number of piano tuners in Chicago or design an app for the elderly. The questions are more grounded and domain-aware.

What I actually got asked:

Product sense: Describe a product you've worked on where you had to balance speed to market against regulatory or compliance constraints. How did you make the call?

Strategy: How would you prioritize a roadmap when one stakeholder is a commercial team with quarterly revenue targets and another is a clinical research team with multi-year timelines? Neither is wrong, both are real.

Metrics: How would you define success for a patient-facing digital health product? What does a good day-7 retention metric mean vs. a bad one in that context?

Behavioral: Tell me about a time you had to kill a feature you believed in because the data didn't support it.

The behavioral questions follow Lilly's values rubric (integrity, excellence, respect, inclusion, innovation) same as for engineering roles.

What I'd prep: read up on Lilly's digital health strategy and their recent launches. They've been building out Connected Care and have acquired a few digital therapeutics assets. If you can reference their actual strategy rather than generic 'healthcare is important' platitudes, you stand out fast. Know what a digital companion diagnostic is.

Comp for director-level PM in Indy 2026: base $165-180k, bonus 20%, RSUs with 3-year vest. Good not FAANG.

4 replies

apm_aisha

The roadmap prioritization question between commercial and clinical is so real. I've never heard it framed that clearly as an interview question before but it's genuinely the hardest ongoing tension in pharma tech PM.

growth_gabe

The day-7 retention question for a patient-facing product is interesting because the 'right' answer is completely different from consumer apps. High engagement might mean the patient isn't getting better. Low engagement might mean they are. Did they want you to work through that tension or just describe the metric?

jordan_pm

They wanted me to work through it. I raised exactly that tension and the interviewer leaned forward a bit. Said something like 'exactly, how do you think about it?' It was the best part of the interview honestly. No clean answer expected, they want to see the thinking.

content_cole

Knowing what a digital companion diagnostic is before walking into that room is the kind of research that separates people who googled 'Lilly interview' from people who actually want to work there.